Brief Communications PlexinA3 Restricts Spinal Exit Points and Branching of Trunk Motor Nerves in Embryonic Zebrafish
نویسندگان
چکیده
Julia Feldner,2,5 Michell M. Reimer,1 Jörn Schweitzer,3 Björn Wendik,3 Dirk Meyer,4 Thomas Becker,1,5 and Catherina G. Becker1,5 1Centre for Neuroscience Research, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh EH9 1QH, United Kingdom, 2Institute for Molecular Bioscience, University of Queensland, St Lucia QLD 4072, Australia, 3Institut für Biologie 1, Universität Freiburg, Freiburg, D-79104, Germany, 4Institut für Molekularbiologie, Leopold-Franzens-Universität Innsbruck, A-6020 Innsbruck, Austria, and 5Zentrum für Molekulare Neurobiologie, University of Hamburg, D-20246 Hamburg, Germany
منابع مشابه
PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish.
The pioneering primary motor axons in the zebrafish trunk are guided by multiple cues along their pathways. Plexins are receptor components for semaphorins that influence motor axon growth and path finding. We cloned plexinA3 in zebrafish and localized plexinA3 mRNA in primary motor neurons during axon outgrowth. Antisense morpholino knock-down led to substantial errors in motor axon growth. Er...
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